Formulation and Physical Quality Testing of Solid Soap From a Combination of Citronella Oil with Patchouli Leaf Oil Againts Staphylococcus aureus Bacteria

Anugrah Riska Pradana, Hasyrul Hamzah, Sinta Ratna Dewi, Wirnawati Wirnawati

Abstract


Bacteria on the skin can cause infections ranging from mild to quite serious. Bacteria that are commonly found on human skin are the pathogenic bacteria Staphylococcus aureus. The choice for making antibacterial solid soap based on active ingredients from patchouli oil and citronella oil is that this oil has inhibitory power in the growth of bacteria on the skin, one of which is Staphylococcus aureus. The aim of this research is to determine how large the inhibition zone is produced by the antibacterial solid soap formulation and to determine the characteristics and physical quality tests of the solid soap preparation combining citronella oil with patchouli leaf oil so that it is safe to use. The method used is a pure experimental method. Data collection was carried out for 4 weeks according to the testing time and then analyzed using the Graphad application. The results of the research on the inhibition zone test used 2 concentrations, namely 50% and 100%, each formulation had different average results, namely at F2 50% the average was 21 mm with a very strong category, at F2 100% the average was 19.5 mm with the strong category, at F3 50% we get an average of 16 mm in the strong category and at F3 100% we get an average of 18.6 mm in the strong category. In the tests that have been carried out, it was concluded that citronella oil and patchouli leaf oil can be made into antiseptic solid soap and can inhibit the growth of Staphylococcus aureus bacteria. The results of testing physical quality characteristics for 4 weeks have met the standard requirements for solid soap.


Keywords


Antiseptic solid soap; citronella oil; patchouli oil; Staphylococcus aureus

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Rusli N, Nurhikma E, Sari EP. Formulasi Sediaan Sabun Padat Ekstrak Daun Lamun (Thalassia hemprichii). War Farm. 10 Oktober 2019;8(2):53–62. 10.46356/wfarmasi. v8i2.96. [2] Hamzah H, Pratiwi SUT, Nur A, Nuryastuti T, Pratama VY, Maulana R. Antibacterial and Antibiofilm Activities of Ternate Blue Pea (Clitoria ternatea) Flower Extract against Staphylococcus aureus. Trop J Nat Prod Res. 1 Februari 2024;8(1). 10.26538/tjnpr/v8i1.40. [3] Hasanah U, Pulungan ASS, Gultom ES. Uji Aktivitas Antibakteri Penyebab Infeksi Pada Kulit Dari Jamur Endofit. J Biosains. Desember 2021;7(3):152–6. https:// doi.org/10.24114/jbio.v7i3.28837. [4] Hamzah H, Pratiwi SUT, Jabbar A, Hafifah AS, Al-Fajri BA, Nurhalisah N. Bioactivity Tracing of the Ethanol Extract of Bajakah Tampala (Spatholobus littoralis Hassk.) Typical Plant of Kalimantan Island as Antibiofilm of Staphylococcus aureus. Open Access Maced J Med Sci. 1 Januari 2023;11(A):8–14. 10.3889/oamjms.2023.10676. [5] Nurhamidin APR, Fatimawali F, Antasionasti I. Uji Aktivitas Antibakteri Ekstrak N-Heksan Biji Buah Langsat (Lansium domesticum Corr) Terhadap Bakteri Staphylococus Aureus dan Klebsiella Pneumoniae. PHARMACON. 24 Februari 2021;10(1):748. 10.35799/ pha.10.2021.32772. [6] Afdhol M, Ahmad M, Hidayat F, Erfando T, Lestari F. Pemanfaatan Daun Serai Wangi sebagai Bahan Baku Pembuatan Minyak Atsiri untuk Peningkatan Ekonomi Masyarakat Desa. Din J Pengabdi Kpd Masy. 30 Juni 2022;6(3):564–9. 10.31849/dinamisia.v6i3.9183. [7] A’yun Q, Hermana B, Kalsum U. Analisis Rendemen Minyak Atsiri Serai Wangi (Cymbopogon nardus (L.) pada Beberapa Varietas. J Pertan Presisi (Journal Precis Agric. 5 Desember 2020;4(2):160–73. 10.35760/jpp.2020. v4i2.3343. [8] Ariska O, Nur BM, Aisyah Y. Karakteristik Mutu, Organoleptik Dan Aktivitas Antibakteri Sabun Padat Transparan Dengan Penambahan Minyak Serai Wangi (Cymbopogon nardus L). J Ilm Mhs Pertan. 1 Februari 2021;6(1):27–36. 10.17969/jimfp.v6i1.16691. [9] Putri MA, Purwati E, Safitri CINH. Formulasi dan Uji Mutu Fisik Sabun Padat Ekstrak Kulit Nanas (Ananas comosus L.). Proceeding Mulawarman Pharm Conf. 2 Agustus 2021;13:275–81. 10.25026/mpc.v13i1.479. [10]Dewi B, Lestari G. Uji Standar Mutu Sifat Fisik Sabun Padat Transparan Minyak Sereh Wangi (Cymbopogon nardus L.) dari VCO (Virgin Coconut Oil). Ocean Biomed J. 27 September 2022;5(1):31–40. 10.30649/obj.v5i1.64. [11] Zulbayu LOMA, Juliansyah R, Firawati F. Optimasi Konsentrasi Sukrosa Terhadap Transparansi Dan Sifat Fisik Sabun Padat Transparan Minyak Atsiri Sereh Wangi (Cymbopogon citratus L.). J Mandala Pharmacon Indones. 30 Desember 2020;6(2):91–6. 10.35311/jmpi.v6i1.60. [12]Setiawati I, Ariani A. Kajian pH Dan Kadar Air Dalam SNI Sabun Mandi Padat di Jabedebog. Pertem dan Present Ilm Stand. 28 Februari 2021;2020:293–300. 10.31153/ ppis.2020.78. [13]Hamzah H, Yudhawan I, Rasdianah N, Setyowati E, Nandini E, Utami S, et al. Clove Oil Has the Activity to Inhibit Middle, Maturation and Degradation Phase of Candida Tropicalis Biofilm Formation. Biointerface Res Appl Chem. 9 Juni 2021;12(2):1507–19. 10.33263/ BRIAC122.15071519. [14]Hamzah H, Hertiani T, Utami Tunjung Pratiwi S, Nuryastuti T. The Inhibition Activity of Tannin on the Formation of Mono-Species and Polymicrobial Biofilm Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. Maj Obat Tradis. 16 Juli 2019;24(2):110. 10.22146/mot.44532. [15]Wijianto B, Hamzah H, Nurhidayah AL, Kemuning GI, Dyas RAA. Characterization of Onchidiid Slug (Onchidium typhae) West Kalimantan Waters as Antibacterials and Antifungal. Borneo J Pharm. 28 Februari 2022;5(1):35– 41. 10.33084/bjop.v5i1.2936.




DOI: https://doi.org/10.18860/jip.v9i1.26885

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