PERANAN ZINC PADA PENANGANAN KASUS PENYAKIT DIARE YANG DIALAMI BAYI MAUPUN BALITA

Riskiyah Riskiyah

Abstract


In Indonesia, diarrhea still is one of top problem public health for causing morbidity and  many deaths. All age groups can be attacked by diarrhea, but severe disease with high mortality especially in infants and toddlers. WHO and UNICEF recommend about management of diarrhea in children namely by adding a supplementation of zinc (Zn) on oral rehydration therapy. Zinc functions in the immune system as a second messenger in signal transduction, cell immunity and nutritional immunity. Zinc also plays an important role in reducing the risk and severity of diarrhea. From some research shows that the effects of therapeutic zinc supplementation can reduce the duration of diarrhea, stool output and stool frequency. The supplementation of 20 mg of zinc per day on the eradication of child diarrhea are less than 5 years and 10 mg per day for infants less than 6 months for 10-14 days. The beneficial effects of zinc supplementation in diarrhea that can speed up the regeneration of the epithelium lining the intestine, increasing the absorption of water and electrolytes in the intestine, increase enzyme levels enterocyte brush-border, and enhance the immune response that can speed up clearance of pathogens from the gut.

Full Text:

PDF

References


. Lindayani S, Azizah R. Hubungan Sarana Sanitasi Dasar Rumah dengan Kejadian diare pada Balita di Desa Ngunut Kabupaten Tulungagung. Jurnal Kesehatan Lingkungan. 2013;7(1):32–7.

Simpson E, Zwisler G dan Moodley M. Survey of Caregivers in Kenya to Assess Perceptions of Zinc As a Treatment for Diarrhea in Young Children and Adherence to Recommended Treatment Behaviors. Journal of Global Health. 2013;3(1):1-7.

. Evayanti N, Purna I dan Aryana I. Faktor-Faktor yang Berhubungan dengan Kejadian Diare pada Balita yang Berobat ke Badan Rumah Sakit Umum Tabanan. Jurnal kesehatan Lingkungan. 2014; 4(2):134-9

.Hakim R, Manoppo J dan Mantik M. Profil Diare Berdarah di Bagian Ilmu Kesehatan Anak BLU.RSUP. Prof.Dr.R.D. Kandou Manado Periode 2008-2011. Jurnal e-Biomedik (eBM). 2013;1(1): 6-11.

Ulfah M, Rustina Y dan Wanda D. Zink Efektif Mengatasi Diare Akut pada Balita. Jurnal Keperawatan Indonesia. 2012;15(2): 137-42

. Suharyono. Diare Akut Klinik dan Laboraturiom. Jakarta: Rineka Cipta; 2008.

. Siswidiasari A dan Yowani. Profil Terapi Obat pada Pasien Rawat Inap dengan Diare Akut Pada Anak Di Rumah Sakit Umum Negara. Jurnal Kimia. 2014;8 (2):183-90.

. Adisasmito W. Faktor Risiko Diare pada Bayi dan Balita di Indonesia: Systematic Review Penelitian Akademik Bidang Kesehatan Masyarakat. MAKARA, Kesehatan. 2007;11(1):1-10.

Manoppo C. Dampak Pemberian Seng dan Probiotik terhadap Lama Diare Akut di Rumah Sakit Prof. Dr. Rd. Kandou Manado. Sari Pediatri. 2010;12(1):17-20.

.Patel A, Dibley M, Mamtani M, Badhoniya N dan Kulkarni H. Influence of Zinc Supplementation in Acute Diarrhea Differs by the Isolated Organism. International Journal of Pediatrics. 2010: 1-9.

Lamberti L, Walker C, Chan K, Jian W dan Black R. Oral Zinc Supplementation for the Treatment of Acute Diarrhea in Children: A Systematic Review and Meta-Analysis. Nutrients. 2013; 5(11):4715-40.

Boas E. Efek Suplementasi Seng terhadap Gejala yang Berhubungan dengan Diare Akut Ringan pada Anak. Jurnal Biomedik (JBM). 2016;8(2):79-82.

.Basuki PP, Sumekar, A. Analisis Kondisi Sosial Demografi, Lingkungan dan Kejadian Diare di Dusun Sagan kecamatan Depok Sleman Yogyakarta. Jurnal Kesehatan “Samodra Ilmu”. 2015;6(2):129-37.

The United Nations Children’s Fund (UNICEF)/World Health Organization (WHO). Diarrhoea: Why Children Are Still Dying and What Can Be Done: New York 2009.

Mullyana dan Kurniasih E. Gambaran Pengetahuan, Pengalaman dan Sikap Ibu terhadap Tatalaksanaan Diare pada Anak Penderita Diare di Ruang Anak Bawah RSUD Dr. Soekardjo Tasikmalaya. Jurnal Kesehatan Bakti Tunas Husada. 2015;13(1):173-80.

.Yusuf S. Profil Diare di Ruang Rawat Inap Anak. Sari Pediatri. 2011; 13(4) 265-70.

.Karuniawati F. Pengaruh Suplementasi Seng dan Probiotik terhadap Durasi Diare Akut Cair Anak. [Tesis]. Semarang: Universitas Diponegoro. 2010.

.Rahmadhani E, Lubis G dan Edison. Hubungan Pemberian Asi Eksklusif dengan Angka Kejadian Diare Akut pada Bayi Usia 0-1 Tahun di Puskesmas Kuranji Kota Padang. Jurnal Kesehatan Andalas. 2013;2(2): 62-6.

.Asuquo E, Georgewill U, Nta I, Enyidah N, Umofia E dan Deekae S. The Effect of Zinc Supplementation on Diarrheal Diseases in Children in The Niger Delta Sub-Region of Nigeria. Open Journal of Preventive Medicine. 2012;2(2):137-40

.Das M dan Das R. Need of Education and Awareness Towards Zinc Supplementation: A Review. International Journal of Nutrition and Metabolism. 2012;4(3):45-50.

.Aliasgharpour dan Mehri. Zn Status in Gastroenteritis Children Under Five Years Old. Int J Med Invest. 2015;4(1):180-2.

.Samani N, Jingxiao Z, Yin Y dan Karki S. Zinc in The Management of Diarrhoe in Children The Age of 5 Years-A Review. Sky Journal of Medicine and Medical Sciences. 2014;2(6):41 -4.

.Oto B, Simadibrata M, Dillon D dan Setiati S. Proportion and Factors Associated with Zinc Deficiency in Acute Diarrhea Patients. The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy. 2011;12(2):73-8.

.Adeniyi S, Akomolafe R, Ojabo C, Eru E dan Olaleye S. Effect of Zinc Treatment on Intestinal Motility in Experimentally Induced Diarrhea in Rats. Niger. J Physiol Sci. 2014; 29:11 –5.

.Lolopayung M, Mukaddas A dan Faustine I. Evaluasi Penggunaan Kombinasi Zink dan Probiotik pada Penanganan Pasien Diare Anak di Instalasi Rawat Inap RSUD Undata Palu Tahun 2013. Online Jurnal Of Natural Science. 2014;3(1):55-64.

.Khoirunnisa S, Andayani T dan Inayati. Analisis Efektivitas dan Biaya Penggunaan Zink pada Anak dengan Diare Akut di Rumah Sakit PKU Muhammadiyah Yogyakarta Tahun 2011. Jurnal Manajemen dan Pelayanan Farmasi. 2012;2(4):250-7.

.Shimelis D, Benti D dan Challi D. Effect of Zinc Supplementation in Treatment of Acute Diarrhoe Among 2-59 months Children Treated in Black Lion Hospital, Addis Ababa, Ethiopia. Ethiop JHealth Dev. 2008;22(2):1870-190.




DOI: https://doi.org/10.18860/jim.v1i1.4119

Refbacks

  • There are currently no refbacks.


 

Editorial Office:

Faculty of Medical and Health Sciences,
Universitas Islam Negeri Maulana Malik Ibrahim
Gedung Ibnu Thufail Lt.1, Jln. Locari, Desa Tlekung, Kota Batu
Phone (+62) 85746163772, (+62) 8563588384, Faximile (+62) 341 558933
e-mail: medicaljournal@uin-malang.ac.id


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.