The journal was initially established under the title SAINTIS: Jurnal Integrasi Sains dan Islam as a multidisciplinary scholarly outlet. In its early phase, the journal published research and technological studies across several scientific disciplines and promoted an integrative perspective between science and Islamic values.
- Initial title and scope: SAINTIS: Jurnal Integrasi Sains dan Islam, covering research and technology in Physics, Chemistry, Biology, Pharmacy, and Medicine, with a thematic emphasis on the integration of Science and Islam.
- Publication period: The journal was actively published until 2012.
- Inactivity: After 2012, publication and editorial operations ceased and the journal remained inactive for an extended period.
- Revitalization and relaunch (2026): In early 2026, the journal was revitalized and relaunched with updated governance, editorial policies, and journal management practices.
- Title change and rebranding: As part of the relaunch, the journal adopted a new title and revised aims and scope as Saintis: Journal of Mathematical Data Science. This relaunch constitutes a title change and rebranding accompanied by a renewed editorial direction.
- Current focus: The journal is now dedicated to mathematical data science, including (but not limited to) mathematical modeling, statistics, data analytics, machine learning, and related computational methods.
While adopting a new identity and scientific focus, the journal maintains its commitment to academic quality, scholarly integrity, and the dissemination of peer-reviewed research.